Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Cathepsin B Substrate III, Fluorogenic
Sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.
MilliporeSigma™ Calbiochem™ Histone Acetyltransferase p300 Inhibitor, C646
Histone Acetyltransferase p300 Inhibitor, C646, CAS 328968-36-1, is a cell-permeable, reversible inhibitor of p300/CBP HAT (Ki = 400nM). Competes with acetyl-CoA for the p300 Lys-CoA binding pocket.
MilliporeSigma™ Calbiochem™ Histone Lysine Methyltransferase Inhibitor
The Histone Lysine Methyltransferase Inhibitor, also referenced under CAS 935693-62-2, controls the biological activity of Histone Lysine Methyltransferase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ MMP-1 Substrate III, Fluorogenic
An excellent quenched fluorescence substrate for MMP-1.
MilliporeSigma™ Calbiochem™ AP-1/NF-κB Dual Inhibitor, SP100030
A cell-permeable, non-toxic, conformationally restricted pyrimidinecarboxamide compound that acts as a potent, reversible T-cell specific inhibitor of both AP-1 and NF-κB transcriptional activation (IC50 = 50
MilliporeSigma™ Calbiochem™ AGE Inhibitor, LR-90
A cell-permeable blocker of advanced glycation end product formation.
MilliporeSigma™ Calbiochem™ InSolution™ AEBSF, Hydrochloride
A 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride in H2O.
MilliporeSigma™ Calbiochem™ Pin1 Inhibitor, DTM
A cell permeable competitive inhibitor of Pin1 (EC50 = 4.1 μM, Ki = 50 nM).
MilliporeSigma™ Calbiochem™ D-Val-Phe-Lys Chloromethyl Ketone, Dihydrochloride
Selective irreversible inhibitor of plasmin with high selectivity for plasmin (IC50 = 100 pM for human plasmin) over urokinase.
MilliporeSigma™ Calbiochem™ BMP Inhibitor II, DMH1
The BMP Inhibitor II, DMH1, also referenced under CAS 1206711-16-1, controls the biological activity of BMP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Caspase-9 Inhibitor III
The Caspase-9 Inhibitor III, also referenced under CAS 403848-57-7, controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Deltamethrin
Synthetic type II pyrethroid. Potent inhibitor of calcineurin. Causes an increase in neurotransmitter release at synapses, and increases intrasynaptosomal Ca2+ levels.
MilliporeSigma™ Calbiochem™ ATR Inhibitor IV
A cell-permeable phenylpyrazine derivative that acts as a potent, ATP-competitive ( Ki 13nM; IC50/[ATP] = 70 nM/50μM and 128 nM/100μM), ATR-selective inhibitor with much reduced or little potency against 4 related PIKKs
MilliporeSigma™ Calbiochem™ Aminopeptidase N/CD13 Inhibitor
The Aminopeptidase N/CD13 Inhibitor controls the biological activity of Aminopeptidase N/CD13. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Proteinase K Inhibitor
Proteinase K Inhibitor is a tetrapeptidyl chloromethyl ketone compound that acts as an active-site-targeting irreversible inhibitor against proteinase K.